Ligand 23 is a cereblon E3 ligase-binding molecule that induces the ubiquitin-proteasomal degradation of transcription factors Ikaros (IKZF1) and Aiolos (IKZF3). This mechanism of action makes it a valuable chemical probe for studying immunology and oncology in both cellular and animal models of disease.
Molekulargewicht:
363.37
Reinheit:
98.49% (May vary between batches)
CAS Nummer:
[444287-56-3]
Formel:
C20H17N3O4
Target-Kategorie:
Ligands for E3 Ligase
Anwendungsbeschreibung:
Solubility: DMSO:55 mg/mL (151.36 mM)
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