c-Src, AZ 12672857, AZ12672857, AZ-12672857, EphB4, EphrinReceptor, Ephrin Receptor
AZ12672857 is a potent and selective EphB4 inhibitor with an IC50 of 1.3 nM. It effectively blocks EphB4 autophosphorylation and cellular proliferation in relevant assays, making it a valuable chemical probe for studying EphB4 signaling in cancer research and angiogenesis, both in vitro and in vivo.