IRE1alpha kinase-IN-1, CAS [[2328097-41-0]]

Produktübersicht

• Artikelname: IRE1alpha kinase-IN-1, CAS [[2328097-41-0]]
• Artikelnummer: BYT-ORB1298021
• Hersteller Artikelnummer: orb1298021
• Alternativnummer: BYT-ORB1298021-1, BYT-ORB1298021-1, BYT-ORB1298021-10, BYT-ORB1298021-100, BYT-ORB1298021-25, BYT-ORB1298021-5, BYT-ORB1298021-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: autophosphorylation, cells, endoplasmic, endoribonuclease, Inhibitor, Inositol requiring enzyme 1, HEK293, oligomerization, IRE1alpha kinaseIN1, IRE-1alpha kinase-IN-1, IRE1alpha kinase-IN-1, IRE1alpha kinase IN 1, IRE1alpha, IRE1a kinase-IN-1, IRE1alpha kinase-IN-1, IRE1, inhibit, reticulum, selectivity

Produktbeschreibung

IRE1alpha kinase-IN-1 is a potent and selective inhibitor of IRE1alpha (ERN1), with an IC50 of 77 nM for kinase and 80 nM for RNase activity, showing 100-fold selectivity over IRE1beta. It blocks ER stress-induced oligomerization and autophosphorylation, making it a valuable tool for studying the unfolded protein response in cellular and animal models of disease.

Produkteigenschaften

• Molekulargewicht: 504.99
• Reinheit: 99.70% (May vary between batches)
• CAS Nummer: [2328097-41-0]
• Formel: C26H26ClFN8
• Target-Kategorie: IRE1

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.98 mM),DMSO:10 mg/mL (19.8 mM)