cancer, Hedgehog, inhibit, Inhibitor, MRT 14, MRT14, MRT-14, Smoothened, Smo
MRT-14 is a potent and selective antagonist of Smoothened (Smo), effectively inhibiting the Hedgehog (Hh) signaling pathway. It is a valuable research tool for studying Hh-driven cancers, suitable for both in vitro cellular assays and in vivo preclinical models of malignancies such as medulloblastoma and basal cell carcinoma.