Tolebrutinib, CAS [[1971920-73-6]]

Produktübersicht

• Artikelname: Tolebrutinib, CAS [[1971920-73-6]]
• Artikelnummer: BYT-ORB1298347
• Hersteller Artikelnummer: orb1298347
• Alternativnummer: BYT-ORB1298347-1, BYT-ORB1298347-10, BYT-ORB1298347-100, BYT-ORB1298347-2, BYT-ORB1298347-200, BYT-ORB1298347-25, BYT-ORB1298347-5, BYT-ORB1298347-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: Bruton tyrosine kinase, Bruton, BTK, Btk, inhibit, multiple, kinase, Inhibitor, PRN2246, PRN-2246, PRN 2246, SAR442168, SAR-442168, SAR 442168, sclerosis, Tolebrutinib, tyrosine

Produktbeschreibung

Tolebrutinib is a potent, selective, and brain-penetrant BTK inhibitor with IC50 values of 0.4 nM and 0.7 nM in Ramos B cells and HMC microglia cells, respectively. It is an orally active compound used in research for multiple sclerosis, demonstrating efficacy in models of central nervous system immunity.

Produkteigenschaften

• Molekulargewicht: 455.51
• Reinheit: 99.20% (May vary between batches)
• CAS Nummer: [1971920-73-6]
• Formel: C26H25N5O3
• Target-Kategorie: BTK

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:100 mg/mL (219.53 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.78 mM)