MTR 106, MTR106, MTR-106, DNA Synthesis, DNASynthesis, RNASynthesis, RNA Synthesis, RNA polymerase I, ZYN 57939, ZYN57939, ZYN-57939
ZYN57939 (MTR-106) is a selective RNA polymerase I inhibitor used in cancer research. It demonstrates potent in vitro activity, such as an IC50 of 0.855 µM against HT-29 human colon cancer cells, and is investigated for its role in targeting dysregulated ribosomal biogenesis in oncology studies.