AS1810722 is a potent, orally bioavailable STAT6 inhibitor with an IC50 of 1.9 nM. This fused bicyclic pyrimidine also inhibits CYP3A4 and is a valuable research tool for studying STAT6-driven pathologies, including allergic asthma and atopic dermatitis, in both cellular and animal models.
Molekulargewicht:
477.51
Reinheit:
99.13% (May vary between batches)
CAS Nummer:
[909561-15-5]
Formel:
C25H25F2N7O
Target-Kategorie:
STAT,Cytochromes P450
Anwendungsbeschreibung:
Solubility: DMSO:62.5 mg/mL (130.89 mM)
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