Epigenetic Reader Domain, EpigeneticReaderDomain, Inhibitor, HATs, HAT, HistoneAcetyltransferase, Histone Acetyltransferase, MCF-7, KIX-KID, inhibit, Naphthol AS E, Naphthol ASE, Naphthol AS-E, nAS-E, CBP, CREB, A549, cancer
Naphthol AS-E (nAS-E) is a small molecule inhibitor that disrupts the KIX-KID protein interaction, thereby suppressing CREB-mediated gene transcription. It is used in biochemical and cellular research to study transcriptional regulation, with applications in both in vitro binding assays and cell-based studies.