Mubritinib, CAS [[366017-09-6]]

Produktübersicht

• Artikelname: Mubritinib, CAS [[366017-09-6]]
• Artikelnummer: BYT-ORB1301053
• Hersteller Artikelnummer: orb1301053
• Alternativnummer: BYT-ORB1301053-5,BYT-ORB1301053-10,BYT-ORB1301053-1,BYT-ORB1301053-25,BYT-ORB1301053-50,BYT-ORB1301053-100
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: PDGFR, JAK1, inhibit, Mubritinib, Inhibitor, HER2/ErbB2, HER1, ErbB-1, Epidermal growth factor receptor, EGFR, FGFR, TAK165, TAK-165, TAK 165

Produktbeschreibung

Mubritinib (TAK-165) is a potent and selective small molecule inhibitor targeting the HER2/ErbB2 tyrosine kinase, demonstrating an IC50 of 6 nM. It has been utilized in preclinical research to investigate HER2-driven cancers, showing antitumor activity in both cellular assays and in vivo xenograft models.

Produkteigenschaften

• Molekulargewicht: 468.47
• Reinheit: 99.87% (May vary between batches)
• CAS Nummer: [366017-09-6]
• Formel: C25H23F3N4O2
• Target-Kategorie: JAK,EGFR,FGFR,PDGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: 10% DMSO+90% Corn Oil:2 mg/mL (4.27 mM),DMSO:35.1 mg/mL (74.92 mM)