PF-04418948, CAS [[1078166-57-0]]

Produktübersicht

• Artikelname: PF-04418948, CAS [[1078166-57-0]]
• Artikelnummer: BYT-ORB1304338
• Hersteller Artikelnummer: orb1304338
• Alternativnummer: BYT-ORB1304338-1, BYT-ORB1304338-10, BYT-ORB1304338-100, BYT-ORB1304338-2, BYT-ORB1304338-25, BYT-ORB1304338-5, BYT-ORB1304338-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: CHO, inhibit, Inhibitor, orally activity, PF 04418948, PF04418948, PF-04418948, PGE2, ProstaglandinReceptor, Prostaglandin Receptor

Produktbeschreibung

PF-04418948 is a highly selective and potent antagonist of the EP2 receptor (IC50 = 16 nM), demonstrating over 2000-fold selectivity against related prostanoid receptors. It effectively inhibits PGE2-induced cAMP signaling in vitro and reverses PGE2-mediated tracheal relaxation ex vivo (IC50 = 2.7 nM), making it a valuable tool for researching EP2 function in inflammation, smooth muscle physiology, and related disease models.

Produkteigenschaften

• Molekulargewicht: 409.41
• Reinheit: 99.45% (May vary between batches)
• CAS Nummer: [1078166-57-0]
• Formel: C23H20FNO5
• Target-Kategorie: Prostaglandin Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.89 mM),DMSO:45 mg/mL (109.91 mM)