R-268712, CAS [[879487-87-3]]

Produktübersicht

• Artikelname: R-268712, CAS [[879487-87-3]]
• Artikelnummer: BYT-ORB1307817
• Hersteller Artikelnummer: orb1307817
• Alternativnummer: BYT-ORB1307817-1,BYT-ORB1307817-5,BYT-ORB1307817-10,BYT-ORB1307817-25,BYT-ORB1307817-50,BYT-ORB1307817-100,BYT-ORB1307817-200
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: renal fibrosis, TGFb, TGF-b/Smad, TGFbeta, TGF-beta, TGF-beta/Smad, TGF-beta Receptor, TGFbeta, TGF-beta, TGF-beta/Smad, TGFbeta/Smad, Smad, R 268712, Thy1 nephritis, R268712, R-268712, Transforming growth factor beta, Transforming growth factor beta receptors, UUO, inhibit, Inhibitor, HFL-1, glomerulonephritis, glomerulosclerosis, Anaplastic lymphoma kinase, Anaplastic lymphoma kinase (ALK), ALK5, ALK tyrosine kinase receptor, CKD, Cluster of differentiation 246, CD246

Produktbeschreibung

R-268712 is a potent and orally bioavailable inhibitor of the TGF-beta type I receptor/ALK5, exhibiting an IC50 of 2.5 nM. This small molecule is a valuable research tool for investigating TGF-beta signaling in fibrosis, oncology, and immunology research, applicable in both cellular and animal models.

Produkteigenschaften

• Molekulargewicht: 363.39
• Reinheit: 99.77% (May vary between batches)
• CAS Nummer: [879487-87-3]
• Formel: C20H18FN5O
• Target-Kategorie: ALK,TGF-beta/Smad

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:250 mg/mL (687.97 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.01 mM)