CX3543, CX-3543, CX 3543, DNASynthesis, DNA Synthesis, DNA/RNA Synthesis, inhibit, Inhibitor, Quarfloxin, RNA polymerase I, RNA pol I, RNA Synthesis, RNASynthesis
Quarfloxin (CX-3543) is a fluoroquinolone-derived anticancer agent that potently inhibits neuroblastoma cell growth by disrupting the nucleolin-G-quadruplex DNA complex in ribosomal DNA. Its application extends to cancer research, where it has been investigated in both in vitro and in vivo models for its mechanism of action and therapeutic potential.