Azvudine, analogue, Human immunodeficiency virus, Inhibitor, Hepatitis C virus, Hepatitis B virus, HBV, HCV Protease, HCVProtease, HCV, HIV Protease, HIV, HIVProtease, HIV-1, HIV-2, FNC, NRTI, mutation, inhibit, resistant, ReverseTranscriptase, Reverse Transcriptase, RO 0622, RO0622, RO-0622
Azvudine (FNC) is a broad-spectrum nucleoside reverse transcriptase inhibitor effective against HIV-1, HIV-2, HBV, and HCV, including NRTI-resistant strains. It demonstrates high in vitro potency with low nanomolar EC50 values and has shown antiviral activity in animal models, supporting its research in virology and antiviral drug development.