AZ1495, CAS [[2196204-23-4]]

Produktübersicht

• Artikelname: AZ1495, CAS [[2196204-23-4]]
• Artikelnummer: BYT-ORB1308616
• Hersteller Artikelnummer: orb1308616
• Alternativnummer: BYT-ORB1308616-1, BYT-ORB1308616-1, BYT-ORB1308616-10, BYT-ORB1308616-100, BYT-ORB1308616-200, BYT-ORB1308616-25, BYT-ORB1308616-5, BYT-ORB1308616-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: cancer, AZ1495, AZ-1495, AZ 1495, CLK4, CLK2, CLK1, diffuse large B-cell lymphoma (DLBCL), Inhibitor, haspin, Haspin Kinase, HaspinKinase, inhibit, IRAK4, IRAK, IRAK-1, IRAK1, IL-1R associated kinase, interleukin-1 receptor associated kinase 1 (IRAK1), interleukin-1 receptor associated kinase 4 (IRAK4), Interleukin-1 receptor associated kinase, weak base

Produktbeschreibung

AZ1495 is a potent and orally bioavailable small molecule inhibitor of IRAK4 (IC50=5 nM) and IRAK1 (IC50=23 nM). It demonstrates research utility in models of diffuse large B-cell lymphoma, particularly for investigating oncogenic signaling driven by the MYD88L265P mutation in both cellular and in vivo studies.

Produkteigenschaften

• Molekulargewicht: 385.5
• Reinheit: 98.81% (May vary between batches)
• CAS Nummer: [2196204-23-4]
• Formel: C21H31N5O2
• Target-Kategorie: CDK,Haspin Kinase,IRAK

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.59 mM),DMSO:10 mg/mL (25.94 mM)