WYE-687, CAS [[1062161-90-3]]

Produktübersicht

• Artikelname: WYE-687, CAS [[1062161-90-3]]
• Artikelnummer: BYT-ORB1685619
• Hersteller Artikelnummer: orb1685619
• Alternativnummer: BYT-ORB1685619-1, BYT-ORB1685619-10, BYT-ORB1685619-100, BYT-ORB1685619-25, BYT-ORB1685619-5, BYT-ORB1685619-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: inhibit, mTOR, Inhibitor, Mammalian target of Rapamycin, p38alpha, p38MAPK, p38 MAPK, PI3K, WYE687, WYE-687, WYE 687, PI3Kalpha, PI3Kgamma, Phosphoinositide 3-kinase, Src

Produktbeschreibung

WYE-687 is a potent and selective ATP-competitive mTOR inhibitor with an IC50 of 7 nM. It effectively suppresses mTORC1 and mTORC2 signaling by inhibiting pS6K(T389) and pAKT(S473), respectively, while showing high selectivity over PI3K isoforms. This inhibitor is a valuable tool for studying mTOR-dependent pathways in cancer and metabolic disease research, both in vitro and in vivo.

Produkteigenschaften

• Molekulargewicht: 528.61
• Reinheit: 99.93% (May vary between batches)
• CAS Nummer: [1062161-90-3]
• Formel: C28H32N8O3
• Target-Kategorie: mTOR,PI3K,p38 MAPK,Src

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: H2O:60.2 mg/mL (113.88 mM),DMSO:60.2 mg/mL (113.88 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.78 mM)