CCR4 antagonist 3 hydrochloride is a potent, selective, and orally bioavailable small molecule inhibitor of CCR4, featuring a novel piperidinyl-azetidine scaffold. It demonstrates inhibitory activity in calcium flux (IC50=22 nM) and chemotaxis assays, supporting its use in oncology research for investigating CCR4-mediated pathways in vitro and in vivo.
CAS Nummer:
[2174938-71-5]
Formel:
C24H27Cl2N7O.xHCl
Target-Kategorie:
CCR,Others
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