CAY10760 is a small molecule inhibitor that disrupts the RAD51-BRCA2 interaction, impairing homologous recombination. It reduces proliferation in pancreatic cancer cell lines, both alone and in combination with PARP inhibitors like olaparib, supporting its research use in studying DNA repair mechanisms and synthetic lethality.
Molekulargewicht:
485.96
CAS Nummer:
[391889-85-3]
Formel:
C28H24ClN3O3
Target-Kategorie:
Others,DNA/RNA Synthesis
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