NHWD-870 is a potent and selective BET bromodomain inhibitor targeting BRD2, BRD3, BRD4, and BRDT. It demonstrates robust anti-tumor activity in vitro and in vivo by inducing apoptosis and inhibiting proliferation, and it disrupts tumor cell-macrophage interactions within the tumor microenvironment.
Molekulargewicht:
491.59
CAS Nummer:
[2115742-03-3]
Formel:
C29H29N7O
Target-Kategorie:
Apoptosis,Epigenetic Reader Domain
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