Acenocoumarol is a chiral oral anticoagulant that inhibits vitamin K epoxide reductase. Its (S)-enantiomer exhibits higher in vitro potency but lower in vivo activity due to extensive first-pass metabolism and faster clearance compared to the more bioavailable (R)-enantiomer. This compound is used in research on thrombosis, pharmacokinetics, and stereoselective drug metabolism.
Molekulargewicht:
353.33
CAS Nummer:
[66556-78-3]
Formel:
C19H15NO6
Target-Kategorie:
Others
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