FR-181877 is a potent, orally bioavailable nonprostanoid prostacyclin (PGI2) receptor agonist. It effectively inhibits ADP-induced human platelet aggregation in vitro (IC50 = 0.081 µM) and demonstrates favorable pharmacokinetics in rats, including a 56% oral bioavailability and a 4.3-hour half-life, supporting its utility in cardiovascular and thrombosis research.
Molekulargewicht:
480.55
CAS Nummer:
[172936-99-1]
Formel:
C30H28N2O4
Target-Kategorie:
Others,Prostaglandin Receptor
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