VUF-10497 is a potent and selective inverse agonist of the histamine H4 receptor (pKi = 7.57) with demonstrated anti-inflammatory activity in rat models. It also exhibits significant affinity for the human histamine H1 receptor. This compound is a valuable pharmacological tool for studying histamine receptor signaling and inflammation in both in vitro and in vivo research.
Molekulargewicht:
373.9
CAS Nummer:
[1080623-12-6]
Formel:
C18H20ClN5S
Target-Kategorie:
Others,Histamine Receptor
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