Silvestrol is a potent and selective inhibitor of eukaryotic initiation factor 4A (eIF4A), disrupting cap-dependent translation. This activity induces both autophagy and caspase-dependent apoptosis, making it a valuable tool for studying oncology, translational control, and cell death mechanisms in vitro and in vivo cancer models.
Molekulargewicht:
654.66
CAS Nummer:
[697235-38-4]
Formel:
C34H38O13
Target-Kategorie:
Apoptosis,Autophagy,PERK,Others
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