SAICAR is a metabolic intermediate in de novo purine synthesis that selectively activates the pyruvate kinase M2 (PKM2) isozyme with an EC50 of 0.3 mM. It is a valuable research tool for studying cancer metabolism, cell proliferation, and the regulation of glycolytic flux in both in vitro and in vivo experimental models.
Molekulargewicht:
454.28
CAS Nummer:
[3031-95-6]
Formel:
C13H19N4O12P
Target-Kategorie:
Endogenous Metabolite,Others
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