Rodatristat ethyl (KAR5585) is a potent, orally bioavailable inhibitor of tryptophan hydroxylase 1 (TPH1). By reducing peripheral serotonin (5-HT) synthesis, it has demonstrated efficacy in preclinical models of pulmonary arterial hypertension (PAH), supporting its investigation in cardiopulmonary research.
Molekulargewicht:
590.04
CAS Nummer:
[1673571-51-1]
Formel:
C29H31ClF3N5O3
Target-Kategorie:
5-HT Receptor,Hydroxylase
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