RO-5963, CAS [[1416663-77-8]]

Produktübersicht

• Artikelname: RO-5963, CAS [[1416663-77-8]]
• Artikelnummer: BYT-ORB1706705
• Hersteller Artikelnummer: orb1706705
• Alternativnummer: BYT-ORB1706705-1, BYT-ORB1706705-1, BYT-ORB1706705-10, BYT-ORB1706705-100, BYT-ORB1706705-200, BYT-ORB1706705-25, BYT-ORB1706705-5, BYT-ORB1706705-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: RO5963, RO-5963, RO 5963, MDMX, Mdm2, p53-MDM2, p53-MDMX, p53

Produktbeschreibung

RO-5963 is a potent small molecule dual inhibitor of the p53-MDM2 and p53-MDMX interactions, with IC50 values of approximately 17 nM and 24 nM, respectively. It is a valuable research tool for reactivating p53 function in cancer cell studies and has demonstrated efficacy in preclinical in vivo tumor models.

Produkteigenschaften

• Molekulargewicht: 518.9
• Reinheit: 99.36% (May vary between batches)
• CAS Nummer: [1416663-77-8]
• Formel: C24H21ClF2N4O5
• Target-Kategorie: Mdm2,p53,E1/E2/E3 Enzyme,MDM-2/p53

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:50 mg/mL (96.36 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.36 mM)