R 121919, R-121919, R121919, NBI 30775, NBI30775, NBI-30775, CRF2, CRF1
R121919 (NBI30775) is a potent small molecule antagonist of the corticotropin-releasing factor receptor 1 (CRF1), also exhibiting activity at the CRF2 receptor and CRF-binding proteins. Its antidepressant and anxiolytic properties make it a valuable research tool for investigating stress-related disorders in both in vitro binding assays and in vivo behavioral models.