Pozanicline is a selective partial agonist of alpha4beta2 neuronal nicotinic acetylcholine receptors (nAChRs), with high affinity for alpha6beta2 and alpha4alpha5beta2 subtypes. It has demonstrated efficacy in reversing nicotine withdrawal-induced cognitive deficits in preclinical models, making it a candidate for research into novel therapies for nicotine addiction.
Molekulargewicht:
192.26
CAS Nummer:
[161417-03-4]
Formel:
C11H16N2O
Target-Kategorie:
AChR
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