GW-311616 hydrochloride is a potent, selective, and orally active inhibitor of human neutrophil elastase (HNE), exhibiting an IC50 of 22 nM and a Ki of 0.31 nM. Its extended duration of action supports its investigation in preclinical models of inflammatory and pulmonary diseases, such as chronic obstructive pulmonary disease (COPD) and bronchiectasis.
Molekulargewicht:
433.99
CAS Nummer:
[197890-44-1]
Formel:
C19H32ClN3O4S
Target-Kategorie:
Others,Serine Protease
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