H3 histone, family 3A, H3 histone, family 3B (H3.3B), H3.3A, H3.3B, H33, H3F3, H3F3A, H3F3B, Histone H3.3
H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA re