E7974 is a synthetic hemiasterlin analog that acts as a potent antimitotic agent by binding to the Vinca site on tubulin, inhibiting polymerization and disrupting microtubule dynamics. It demonstrates preferential affinity for the betaIII-tubulin isotype and has shown antitumor activity in preclinical in vivo models, supporting its investigation in cancer research.
Molekulargewicht:
437.62
CAS Nummer:
[610787-07-0]
Formel:
C24H43N3O4
Target-Kategorie:
Others
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