HDAC/BET-IN-1 is a dual-acting inhibitor targeting histone deacetylases (HDAC1/6) and bromodomain protein BRD4 with submicromolar potency. It demonstrates significant antileukemic activity in cellular assays, making it a valuable chemical probe for oncology research, particularly in studying epigenetic pathways and their role in hematological malignancies.
Molekulargewicht:
604.71
CAS Nummer:
[2757573-68-3]
Formel:
C29H40N4O8S
Target-Kategorie:
HDAC
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