Norartocarpetin is a potent tyrosinase inhibitor (IC50 0.47 µM) with food antibrowning applications and exhibits anticancer activity against NCI-H460 lung carcinoma cells (IC50 22 µM). Its antiproliferative mechanism involves inhibiting the Ras/Raf/MAPK pathway, inducing mitochondrial apoptosis, causing S-phase arrest, and suppressing cell migration and invasion in vitro.
Molekulargewicht:
286.24
CAS Nummer:
[520-30-9]
Formel:
C15H10O6
Target-Kategorie:
Others,MAPK,Raf,Ras,Apoptosis,Tyrosinase
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