EGFR/C797S-IN-1 is a potent and selective small molecule inhibitor of the EGFR C797S mutation with an IC50 of 0.128 µM. It demonstrates dose-dependent suppression of p-EGFR, leading to anti-proliferative activity in vitro and anti-tumor efficacy in vivo, making it a valuable tool for studying resistance mechanisms in non-small cell lung cancer.
Molekulargewicht:
470.56
CAS Nummer:
[2378188-21-5]
Formel:
C28H30N4O3
Target-Kategorie:
EGFR,Others
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