c-Met/HDAC-IN-2 is a dual-action small molecule with potent inhibitory activity against c-Met (IC50=5.40 nM) and HDAC1 (IC50=18.49 nM). It demonstrates robust anti-proliferative effects in vitro, inducing cell cycle arrest and apoptosis in cancer cell lines like HCT-116, supporting its investigation for overcoming therapeutic resistance.
Molekulargewicht:
623.66
CAS Nummer:
[2740495-53-6]
Formel:
C34H33N5O7
Target-Kategorie:
HDAC,Others,c-Met/HGFR,Apoptosis
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