SARS-CoV-2 Mpro-IN-4 is a dual-target inhibitor of the viral Main Protease (Mpro, IC50=900 nM) and host Cathepsin L (CatL, IC50=60 nM). It potently inhibits viral replication in cellular assays (IC50=8.2 nM in hACE2-A549 cells), making it a valuable chemical probe for studying coronavirus entry and replication mechanisms in vitro.
Molekulargewicht:
534.65
Formel:
C30H38N4O5
Target-Kategorie:
Virus Protease,Others,SARS-CoV
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