m-PEG4-Br is a cleavable linker utilized in constructing antibody-drug conjugates (ADCs) like those employing Trastuzumab and MMAE. Its distal placement from the payload modulates conjugate hydrophilicity and binding properties, which are critical parameters evaluated in both in vitro cytotoxicity assays and in vivo efficacy studies for targeted cancer therapy.
Molekulargewicht:
271.15
CAS Nummer:
[110429-45-3]
Formel:
C9H19BrO4
Target-Kategorie:
ADC Linker,PROTAC Linker
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