AC-099 (compound 3) serves as a selective full agonist at NPFF2R (EC50 = 1189 nM) and a partial agonist at NPFF1R (EC50 = 2370 nM). It has been shown to mitigate hypersensitivity induced by spinal nerve ligation in rats.
Molekulargewicht:
264.64
CAS Nummer:
[849459-88-7]
Formel:
C9H8ClF3N4
Target-Kategorie:
Others
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