TAT-PDHPS1 is a cell-permeable peptide inhibitor of YAP signaling that acts by binding PTPA to activate PP2A, leading to YAP phosphorylation. It has demonstrated efficacy in inhibiting ovarian cancer cell proliferation in vitro and reducing tumor growth in mouse xenograft models, supporting its use in oncology research.
Molekulargewicht:
3744.32
Formel:
C156H280N62O45
Target-Kategorie:
YAP,Others
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