LL-K9-3 is a selective hydrophobic tag (HyT)-based degrader that induces the synchronous degradation of the CDK9-cyclin T1 complex. This mechanism effectively reduces AR and cMyc expression in cellular models like 22RV1 cells, providing a tool for oncology research targeting transcriptional dependencies in cancers.
Molekulargewicht:
683.94
CAS Nummer:
[2809353-52-2]
Formel:
C31H49N5O6S3
Target-Kategorie:
PROTACs,Others,Apoptosis,c-Myc,CDK
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