SARS-CoV-2-IN-27, a diphosphate ester featuring a C6 alkyl chain and extended-length molecular tweezers, demonstrates antiviral efficacy, with IC50 values of 1.0 µM and 1.7 µM against SARS-CoV-2 activity and spike pseudoparticle transduction, respectively. Additionally, it disrupts liposomal membranes, evidenced by an EC50 of 6.5 µM.
Molekulargewicht:
894.97
Formel:
C54H56O8P2
Target-Kategorie:
Others,SARS-CoV
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