Lys-CoA TFA is a potent and selective p300 histone acetyltransferase (HAT) inhibitor, with an IC50 of 50-500 nM and over 100-fold selectivity versus PCAF. It effectively blocks p300-dependent transcriptional activation and is a valuable chemical probe for studying epigenetic regulation in cancer and cellular differentiation research in vitro.
Molekulargewicht:
1108.82
Formel:
C33H54F3N10O21P3S
Target-Kategorie:
Histone Acetyltransferase,Others
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