BQ-123 TFA is a potent and selective ETA receptor antagonist (IC50 = 7.3 nM) that inhibits endothelin-1-induced vascular smooth muscle cell proliferation in vitro and lowers blood pressure in rat hypertension models in vivo, making it a key research tool for studying cardiovascular diseases.
Molekulargewicht:
724.72
Formel:
C33H43F3N6O9
Target-Kategorie:
Endothelin Receptor,Others
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