Sanggenon G is a cell-permeable small molecule that potently inhibits XIAP by binding to its BIR3 domain with 34.26 µM affinity, promoting caspase activation. This compound is a useful research tool for studying apoptosis mechanisms and has been employed in both in vitro and in vivo cancer research models to investigate sensitization to cell death.
Molekulargewicht:
694.72
CAS Nummer:
[85698-31-3]
Formel:
C40H38O11
Target-Kategorie:
Caspase,Others,IAP
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