GB-110 hydrochloride is a potent, orally bioavailable nonpeptide agonist for protease-activated receptor 2 (PAR2). It selectively induces PAR2-mediated intracellular Ca2+ mobilization in vitro, as demonstrated in HT29 cells with an EC50 of 0.28 µM. This compound is a valuable tool for investigating PAR2 signaling in inflammation, pain, and cancer research contexts.
Molekulargewicht:
645.23
Formel:
C33H49ClN6O5
Target-Kategorie:
Protease-activated Receptor,Others
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