SR 142948 dihydrochloride is a potent, brain-penetrant, and selective non-peptide antagonist of the neurotensin receptor (NTR1). It effectively blocks neurotensin-mediated signaling in cellular assays (e.g., inositol monophosphate formation in HT-29 cells) and inhibits NT-induced behavioral responses like hypothermia and analgesia in vivo, making it a valuable research tool for studying psychiatric and neurological disorders.
Molekulargewicht:
758.77
Formel:
C39H53Cl2N5O6
Target-Kategorie:
Neurotensin Receptor,Others
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
