Fradafiban (BIBU-52) hydrochloride is a potent, nonpeptide antagonist of the platelet integrin GP IIb/IIIa, exhibiting a Kd of 148 nM for the human receptor. It is a valuable research tool for studying thrombosis and platelet aggregation mechanisms in both in vitro assays and in vivo animal models of cardiovascular disease.
Molekulargewicht:
403.86
Formel:
C20H22ClN3O4
Target-Kategorie:
Others,Integrin
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