Trimetazidine-N-oxide, the primary active metabolite of Trimetazidine, acts as a potent and selective inhibitor of long-chain 3-ketoacyl-CoA thiolase (IC50: 75 nM). This small molecule exhibits antioxidant, anti-inflammatory, and gastroprotective activities, supporting its use in cardiovascular and metabolic research involving both in vitro enzyme assays and in vivo models.
Molekulargewicht:
282.34
CAS Nummer:
[1644530-89-1]
Formel:
C14H22N2O4
Target-Kategorie:
Drug Metabolite,Others
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