2-O-Methylguanosine-5-O-triphosphate sodium Preis auf Anfrage

Produktübersicht

• Artikelname: 2-O-Methylguanosine-5-O-triphosphate sodium Preis auf Anfrage
• Artikelnummer: BYT-ORB2276817
• Hersteller Artikelnummer: orb2276817
• Alternativnummer: BYT-ORB2276817-5,BYT-ORB2276817-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien

Produktbeschreibung

2-O-Methylguanosine-5-O-triphosphate (2-methyl GTP) acts as an inhibitor targeting the hepatitis C virus (HCV) non-structural protein 5B (NS5B, with an IC50 of 3.5 µM), and serves as an active metabolite of the prodrug IDX184 through a 2-methylguanosine intermediate transformation. Additionally, at a concentration of 50 µM, it promotes tubulin polymerization. Notably, levels of 2-methyl GTP are reduced in the tumoral tissues of patients with hepatocellular carcinoma in comparison to the adjacent normal tissues.

Produkteigenschaften

• Molekulargewicht: 625.13
• Formel: C11H14N5O14P3.4Na
• Target-Kategorie: Others