Tamapin TFA, a venom peptide isolated from the Indian red scorpion (Mesobuthus tamulus), selectively targets and blocks small conductance Ca(2+)-activated K(+) (SK) channels, particularly the SK2 subtype (Potassium Channel). It is known to inhibit SK channel-mediated currents in the hippocampal pyramidal neurons.
Molekulargewicht:
3458.11 (free base)
Formel:
C146H238N44O41S6.xC2HF3O2
Target-Kategorie:
Potassium Channel
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