Scorpion toxin Tf2, a beta-scorpion toxin first identified in the venom of the Brazilian scorpion Tityus fasciolatus, acts as an activator of the neuronal voltage-gated sodium (Nav) subtype Nav1.3, associated with epilepsy and nociception. It increases hNav1.3 activation voltage, prompting channel opening at resting membrane potentials.
Molekulargewicht:
6953.86
Formel:
C309H438N80O87S9
Target-Kategorie:
Sodium Channel
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